Total citations: 311, h-index: 9, i10-index: 9 (According to Google Scholar, accessed on 17 Jun 2024.)
*Based on Journal Citation Reports™ 2022, Clarivate, and CiteScore™ 2023, Elsevier. Data accessed on 17 Jun 2024.
Selected representative journal articles
Lutein Modulates Cellular Functionalities and Regulates NLRP3 Inflammasome in a H2O2-Challenged Three-Dimensional Retinal Pigment Epithelium Model
Journal of Agricultural and Food Chemistry | 2024
Liu, H., Wu, C., Hu, S., Leng, B., Lou, X., Liu, Z., Su, X., & Huang, D.
- This study highlights the potential use of 3D cell culture strategies to gain molecular insights into the role of bioactive compounds in retinal health.
- It has provided valuable insights into the molecular mechanisms, which identify lutein as a regulator of the NLRP3 inflammasome and play a crucial role in mediating inflammatory responses.
- The study expands our understanding of lutein’s protective role in retinal health and also sheds light on the molecular pathways that underlie its function.
JCR - Q1, Impact Factor: 6.1, Rank 6/58, Agriculture, Multidisciplinary; CiteScore - Q1, Biotechnology
Protective Effects of Lutein Against Phone Screen Light-Induced Damage on 3D Bioprinted Retinal Pigment Epithelium Monolayers
Journal of Functional Foods | 2024, 116: 106216
Liu, H., Chen, R., Chen, Y., Lou, X., Liu, Z., Su, X., & Huang, D.
- The first 3D RPE monolayer was used for studying dietary antioxidants.
- Phone screen light reduced cell viability and increased oxidative stress levels.
- Lutein promoted cell survival by reducing oxidative stress and improved barrier and phagocytosis functions of light-damaged RPE monolayer.
JCR - Q1, Impact Factor: 5.6, Rank 27/142, Food Science & Technology; CiteScore - Q1, Biotechnology
Electrohydrodynamic Jet Printed Ultrathin Polycaprolactone Scaffolds for Retinal Pigment Epithelial Tissue Engineering
International Journal of Bioprinting | 2022, 8(3)
Liu, H., Wu, F., Chen, R., Chen, Y., Yao, K., Liu, Z., Parikh, B., Jing, L., Liu, T., Su, X., Sun, J., & Huang, D.
- EHDJ printing can fabricate scaffolds that mimic Bruch’s membrane by promoting maturation of RPE cells to form a polarized and functional monolayered epithelium
- Great potential to applicate as an in vitro model for studying retinal diseases and treatment methods.
IF: 8.4, Q1, Rank 12/96, Engineering/Biomedical; 7/45, Materials Science, Biomaterials
An Overview of Scaffolds for Retinal Pigment Epithelium Research
Procedia Manufacturing | 2021, 51
Liu, H., Jing, L., Sun, J., & Huang, D.
- This overview outlines the most recent fabrication progresses using these materials for RPE scaffolds, including both in vitro and in vivo trials, and the challenges in building a whole tissue model construct and transplantation.
- Additive manufacturing technologies at micrometer- and nanometer-scale are proposed as promising methods to build biomimetic RPE scaffolds in the current studies.
Influence of Electrohydrodynamic Jetting Parameters on the Morphology of PCL Scaffolds
International Journal of Bioprinting | 2017, 3(1)
Liu, H., Vijayavenkataraman, S., Wang, D., Jing, L., Sun, J., & He, K.
- EHDJ printing could be used for fabrication of multi-layer scaffolds with various morphology and resolution that could be achieved by tuning key process parameters.
- Arrayed diverse structures like the coiled scaffolds can potentially be applied in soft tissue repair and 3D cell culture in regenerative medicine.
IF: 8.4, Q1, Rank 12/96, Engineering/Biomedical; 7/45, Materials Science, Biomaterials
Full publication list
[18] Liu, H., Wu, C., Hu, S., Leng, B., Lou, X., Liu, Z., Su, X., & Huang, D. (2024). Lutein modulates cellular functionalities and regulates NLRP3 inflammasome in an H2O2-challenged 3D retinal pigment epithelium model. Journal of Agricultural and Food Chemistry, 116, 106216. [Full text]
[17] Liu, H., Chen, R., Chen, Y., Lou, X., Liu, Z., Su, X., & Huang, D. (2024). Protective effects of lutein against phone screen light-induced damage on 3D bioprinted retinal pigment epithelium monolayers. Journal of Functional Foods, 116, 106216. [Full text]
[16] Lou, X., Shu, W., Wang, Y., Guo, C., Liu, H., & Yang, H. (2024). Effect of slightly acidic electrolysed water against Shewanella baltica in phosphate-buffered saline and on golden pomfret sticks. Food Control, 156, 110131. [Full text]
[15] Su, L., Jing, L., Zeng, X., Chen, T., Liu, H., Kong, Y., Wang, X., Yang, X., Fu, C., Sun, J., & Huang, D. (2022). 3D-printed prolamin scaffolds for cell-based meat culture. Advanced Materials, in-print. [Full text]
[14] Liu, H. (2022). Electrohydrodynamic jet-printed scaffolds for engineering retinal pigment epithelium monolayer tissue. National University of Singapore. [Full text]
[13] Liu, H., Wu, F., Chen, R., Chen, Y., Yao, K., Liu, Z., … & Huang, D. (2022). Electrohydrodynamic jet-printed ultrathin polycaprolactone scaffolds mimicking Bruch’s membrane for retinal pigment epithelial tissue engineering. International Journal of Bioprinting, 8(3). [Full text]
[12] Yao, K., Sun, J., Huang, K., Jing, L., Liu, H., Huang, D., & Jude, C. (2021). Analyzing cell-scaffold interaction through unsupervised 3D nuclei segmentation. International Journal of Bioprinting, 8(1): 495. [Full text]
[11] Jing, L., Wang, X., Leng, B., Zhan, N., Liu, H., Wang, S., … & Huang, D. (2021). Engineered nanotopography on the microfibers of 3D-printed PCL scaffolds to modulate cellular responses and establish an in vitro tumor model. ACS Applied Bio Materials, 4(2), 1381-1394. [Full text]
[10] Jing, L., Sun, M., Xu, P., Yao, K., Yang, J., Wang, X., Liu, H., … & Huang, D. (2021). Noninvasive in vivo imaging and monitoring of 3D-printed polycaprolactone scaffolds labeled with an NIR region II fluorescent dye. ACS Applied Bio Materials, 4(4), 3189-3202. [Full text]
[9] Liu, H., Jing, L., Sun, J., & Huang, D. (2021). An overview of scaffolds for retinal pigment epithelium research. Procedia Manufacturing, 53, 492-499. [Full text]
[8] Jing, L., Sun, J., Liu, H., Wang, X., & Huang, D. (2021). Using plant proteins to develop composite scaffolds for cell culture applications. International Journal of Bioprinting, 7(1). [Full text]
[7] Sun, J., Jing, L., Liu, H., & Huang, D. (2020). Generating nanotopography on PCL microfiber surface for better cell-scaffold interactions. Procedia Manufacturing, 48, 619-624. [Full text]
[6] Wang, D., Jing, L., Liu, H., Huang, D., & Sun, J. (2019). Microscale scaffolds with diverse morphology via electrohydrodynamic jetting for in vitro cell culture application. Biomedical Physics & Engineering Express, 5(2). [Full text]
[5] Jing, L., Wang, X., Liu, H., Lu, Y., Bian, J., Sun, J. & Huang, D. (2018). Zein increases the cytoaffinity and biodegradability of scaffolds 3D-printed with zein and poly(ε-caprolactone) composite ink. ACS Applied Materials & Interfaces, 10(22), 18551-18559. ink. ACS Applied Materials & Interfaces, 10(22), 18551-18559. [Full text]
[4] Liu, H. (2018). 3D printing of silicone meniscus implant via extrusion technique. Nanyang Technological University. [Full text]
[3] Luis, E., Liu, H., Juha, S., Yeong, W. (2018) A review of medical silicone 3D-printing technologies and clinical applications. Journal of Orthopedic Research and Therapy. [Full text]
[2] Sun, J., Vijayavenkataraman, S., & Liu, H.. (2017). An overview of scaffold design and fabrication technology for engineered knee meniscus. Materials, 10(1), 29. [Full text]
[1] Liu, H., Vijayavenkataraman, S., Wang, D., Jing, L., Sun, J., & He, K. (2017). Influence of electrohydrodynamic jetting parameters on the morphology of PCL scaffolds. International Journal of Bioprinting, 3(1), 009. [Full text]
Patents
- “Electro-fluid jetting device and method for printing a three-dimensional biological scaffold”, Sun J, Shu Z, Liu H, Wang D, Fuh JYH, Wu Y. Chinese Patent. CN 107718531 A.
- “Multi-scale and diverse coiled pattern scaffold fabrication using electrohydrodynamic jetting”, Sun J, Wang D, Liu H, Wang YB, Wang Y. Chinese Patent. Application number: 201710250386.5 (pending).